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SAPOSITORYS....Why the butt? When the body absorbs compounds into the blood stream, it does so best via its mucus membranes — any of the “wet” tissues in the body, like the mouth, nasal passages, lung, stomach, urethra, and rectum — but they don’t all absorb substances equally. In an interview with the Canadian Press, Mikhail Kogan, medical director of the Center for Integrative Medicine at George Washington University in Washington, D.C., pointed out that the lungs just aren’t very good at this, and neither, for that matter, is the stomach, which is full of gastric acids that interfere with absorption. Smoking or eating marijuana, therefore, simply aren’t efficient ways of administering it. More reasons for doctors to try an alternative route. There seems to be a lot more control in the dosage of anally absorbed marijuana. “Rectally is actually a lot more preferred because of the volume of absorption,” Kogan said. “You can put a lot more and it gets absorbed a lot better, but not everybody is open to this way of administration. ”Currently, suppositories are made by dissolving cannabis extract in an oil or butter (as anyone who’s cooked their own edibles knows, the cannabinoids are fat-soluble). Putting the finished product in the rectum is said to have rapid systemic effects as well as reduce the drug’s psychoactive effects, which is ideal for people who use marijuana for medical and not recreational reasons. Within the marijuana community, more people are recognizing rectal weed’s potential, thanks in part to the efforts of an organization called Back Door Medicine, which aims to educate the public about the advantages of putting marijuana in the anus. While further tests will be needed to show just how much safer rectal marijuana is compared to weed smoke, anyone curious to experiment on themselves can simply try making their own.